Unmasking the roles of the tachykinins in the human brain S. Newton and N. M. Page The tachykinins are a family of peptides that have biological actions in the human brain. They are implicated in the control of several autonomic, affective and higher cerebral functions and in the pathophysiology of some neurogenerative and psychiatric disorders. We have discovered new members of this group of peptides that are also active in the brain. Here, we review our current understanding of the roles of the tachykinins as neuro- and immunomodulators in the brain. Tachykinin peptide endokinin brain newton_page2007.pdf